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17 April 2014 12:48 pm ,
Vol. 344 ,
Using the two high-quality genomes that exist for Neandertals and Denisovans, researchers find clues to gene activity...
A new report from the Intergovernmental Panel on Climate Change (IPCC) concludes that humanity has done little to slow...
Astronomers have discovered an Earth-sized planet in the habitable zone of a red dwarf—a star cooler than the sun—500...
Three years ago, Jennifer Francis of Rutgers University proposed that a warming Arctic was altering the behavior of the...
Officials last week revealed that the U.S. contribution to ITER could cost $3.9 billion by 2034—roughly four times the...
An experimental hepatitis B drug that looked safe in animal trials tragically killed five of 15 patients in 1993. Now,...
- 17 April 2014 12:48 pm , Vol. 344 , #6181
- About Us
A Bloody Measure
18 July 1997 7:00 pm
In search of tiny amounts of antibodies, medical physicist Rosalyn Yalow developed a technique that came up very big for biomedical researchers. Tomorrow is the 76th birthday of the Nobel laureate who co-developed the radioimmunoassay, a technique used widely to measure small amounts of substances in blood or other biological fluids.
In the 1950s Yalow and her physician co-worker, Solomon Berson, discovered new ways to use radioactive isotopes to study physiology. While investigating adult-onset diabetes, they found evidence that diabetics being treated with animal insulin developed antibodies against the foreign protein, which was believed to be too small to elicit such an immune response.
To verify their finding, Yalow and Berman developed the radioimmunoassay to detect insulin antibodies at minute concentrations. For this work, Yalow shared the 1977 Nobel Prize in physiology or medicine with Andrew Schally and Roger Guillemin, who used the radioimmunoassay to make breakthroughs in understanding brain hormones.
[Source: Emily McMurray, Ed., Notable Twentieth Century Scientists (Gale Research Inc., ITP, 1995).]