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Magdalena Koziol, a former postdoc at Yale University, was the victim of scientific sabotage. Now, she is suing the...
Antiretroviral drugs can protect people from becoming infected by HIV. But so-called pre-exposure prophylaxis, or PrEP...
Two studies show that eating a diet low in protein and high in carbohydrates is linked to a longer, healthier life, and...
Considered an icon of conservation science, researchers at World Wildlife Fund (WWF) headquarters in Washington, D.C.,...
The new atlas, which shows the distribution of important trace metals and other substances, is the first product of...
Early in April, the first of a fleet of environmental monitoring satellites will lift off from Europe's spaceport in...
Since 2000, U.S. government health research agencies have spent almost $1 billion on an effort to churn out thousands...
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A Bloody Measure
18 July 1997 7:00 pm
In search of tiny amounts of antibodies, medical physicist Rosalyn Yalow developed a technique that came up very big for biomedical researchers. Tomorrow is the 76th birthday of the Nobel laureate who co-developed the radioimmunoassay, a technique used widely to measure small amounts of substances in blood or other biological fluids.
In the 1950s Yalow and her physician co-worker, Solomon Berson, discovered new ways to use radioactive isotopes to study physiology. While investigating adult-onset diabetes, they found evidence that diabetics being treated with animal insulin developed antibodies against the foreign protein, which was believed to be too small to elicit such an immune response.
To verify their finding, Yalow and Berman developed the radioimmunoassay to detect insulin antibodies at minute concentrations. For this work, Yalow shared the 1977 Nobel Prize in physiology or medicine with Andrew Schally and Roger Guillemin, who used the radioimmunoassay to make breakthroughs in understanding brain hormones.
[Source: Emily McMurray, Ed., Notable Twentieth Century Scientists (Gale Research Inc., ITP, 1995).]