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24 April 2014 11:45 am ,
Vol. 344 ,
Major climate data sets have underestimated the rate of global warming in the last 15 years owing largely to poor data...
The tsetse fly is best known as the vector for the trypanosome parasites that cause sleeping sickness and a disease in...
The National Institutes of Health is revising its "two strikes" rule, which allowed researchers only one chance to...
By stabilizing the components of retromers, molecular complexes that act like recycling bins in cells, a recently...
Fossil fuels power modern society by generating heat, but much of that heat is wasted. Semiconductor devices called...
Researchers are gaining insights into what made Supertyphoon Haiyan so powerful and devastating through post-storm...
Millions around the world got a first-hand look at what it was like to be in Tacloban while it was pummeled by...
- 24 April 2014 11:45 am , Vol. 344 , #6182
- About Us
Anatomy of an Adrenaline Rush
19 November 1997 8:00 pm
How stress hormones unleash a surge of energy was explained by Earl Sutherland, a biochemist born 82 years ago today. Sutherland found that adrenaline accelerates the breakdown of sugar in the liver to provide quick energy during moments of stress. He later discovered that the hormone stimulates individual cells in two steps. First, it latches onto a receptor on the cell surface. The receptor then triggers the release inside the cell of a second signal: a molecule called cyclic AMP (cAMP). Sutherland then determined that cAMP has a larger role, serving as an intermediary for many hormones regulating metabolism in both simple and complex organisms. For this fundamental breakthrough, he received the Nobel Prize in physiology or medicine in 1971. He died 3 years later.
[Source: Emily McMurray, Ed. Notable Twentieth Century Scientists. Gale Research Inc. ITP. 1995.]