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10 April 2014 11:44 am ,
Vol. 344 ,
The Pyrenean ibex, an impressive mountain goat that lived in the central Pyrenees in Spain, went extinct in 2000. But a...
Tight budgets are forcing NASA to consider turning off one or more planetary science projects that have completed their...
Ebola is not a stranger to West Africa—an outbreak in the 1990s killed chimpanzees and sickened one researcher. But the...
In an as-yet-unpublished report, an international panel of geoscientists has concluded that a pair of deadly...
Tropical disease experts tried and failed before to eradicate yaws, a rare disfiguring disease of poor countries. Now,...
Since 2002, researchers have reported that agricultural communities in the hot and humid Pacific Coast of Central...
Balkan endemic kidney disease surfaced in the 1950s and for decades defied attempts to finger the cause. It occurred...
- 10 April 2014 11:44 am , Vol. 344 , #6180
- About Us
Anatomy of an Adrenaline Rush
19 November 1999 8:00 pm
How stress hormones unleash a surge of energy was explained by Earl Sutherland, a biochemist born 84 years ago today
. Sutherland found that adrenaline accelerates the breakdown of sugar in the liver to provide quick energy during moments of stress. He later discovered that the hormone stimulates individual cells in two steps. First, it latches onto a receptor on the cell surface. The receptor then triggers the release inside the cell of a second signal: a molecule called cyclic AMP (cAMP). Sutherland then determined that cAMP has a larger role, serving as an intermediary for many hormones regulating metabolism in both simple and complex organisms. For this fundamental breakthrough, he received the Nobel Prize in physiology or medicine in 1971. He died 3 years later.
[Source: Emily McMurray, Ed. Notable Twentieth Century Scientists. Gale Research Inc. ITP. 1995.]