- News Home
6 March 2014 1:04 pm ,
Vol. 343 ,
Magdalena Koziol, a former postdoc at Yale University, was the victim of scientific sabotage. Now, she is suing the...
Antiretroviral drugs can protect people from becoming infected by HIV. But so-called pre-exposure prophylaxis, or PrEP...
Two studies show that eating a diet low in protein and high in carbohydrates is linked to a longer, healthier life, and...
Considered an icon of conservation science, researchers at World Wildlife Fund (WWF) headquarters in Washington, D.C.,...
The new atlas, which shows the distribution of important trace metals and other substances, is the first product of...
Early in April, the first of a fleet of environmental monitoring satellites will lift off from Europe's spaceport in...
Since 2000, U.S. government health research agencies have spent almost $1 billion on an effort to churn out thousands...
- 6 March 2014 1:04 pm , Vol. 343 , #6175
- About Us
8 December 1999 7:00 pm
Today is the 52nd birthday of Thomas Cech, a biochemist who helped discover catalytic RNA. In the process, Cech and his colleagues overturned conventional wisdom about the interactions between DNA, RNA, and protein enzymes in the evolution and reproduction of life.
Cech wanted to know how the genetic code in DNA is copied to an RNA template--a process called transcription--and how certain parts of the code are spliced out. During an experiment in 1981, Cech and his colleague Arthur Zaug were surprised to learn that protozoan RNA appeared to splice itself without the help of any enzymes. Their announcement in 1982 of the existence of a "ribozyme"--an RNA molecule capable of catalyzing chemical reactions--upset beliefs about the nature of enzymes, but soon other catalytic RNAs were discovered.
The finding bolstered the idea that RNA was the first important biological molecule to arise in the "primordial soup" and to spur the evolution of life. Catalytic RNAs are now being engineered and tested as potential drugs for treating viral infections. Cech received a share of the 1989 Nobel Prize in chemistry. He currently heads a lab at the University of Colorado, Boulder, but was appointed president of the Howard Hughes Medical Institute in Chevy Chase, Maryland this year (ScienceNOW, 24 March), where he will take office on 1 January 2000.
[Source: Emily McMurray, Ed., Notable Twentieth Century Scientists (Gale Research Inc., ITP, 1995).]