Fighting Allergies, Designing With Nature

28 April 2000 5:00 pm

Hay fever season is an appropriate time for this year's Japan Prize: Kimishige Ishizaka, 74, the man who discovered immunoglobulin E--an infection-fighting protein implicated in allergic responses--today won 50 million yen ($485,000) for his work on "host defense." Ishizaka, president emeritus of the La Jolla Institute for Allergy and Immunology in California, developed a method of detecting minute quantities of proteins in solutions that is now a standard tool in studying cytokines, signaling proteins released by cells.

The year's other prize, for city planning, went to Scottish-born landscape architect Ian McHarg, 79, professor emeritus at the University of Pennsylvania, Philadelphia, and author of a pathbreaking 1969 book, Design With Nature. He was honored for incorporating ecological concerns in community and regional planning.

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