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5 December 2013 11:26 am ,
Vol. 342 ,
An animal rights group known as the Nonhuman Rights Project filed lawsuits in three New York courts this week in an...
Researchers have been hot on the trail of the elusive Denisovans, a type of ancient human known only by their DNA and...
Thousands of scientists in the Russian Academy of Sciences (RAS) are about to lose their jobs as a result of the...
Dyslexia, a learning disability that hinders reading, hasn't been associated with deficits in vision, hearing, or...
Exotic, elusive, and dangerous, snakes have fascinated humankind for millennia. They can be hard to find, yet their...
Researchers have sequenced and analyzed the first two snake genomes, which represent two evolutionary extremes. The...
Snake venoms are remarkably complex mixtures that can stun or kill prey within minutes. But more and more researchers...
At age 30, Dutch biologist Freek Vonk has built up a respectable career as a snake scientist. But in his home country,...
- 5 December 2013 11:26 am , Vol. 342 , #6163
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Rat Race for Next Mammalian Genome
23 May 2000 6:00 pm
The rat will be the next target for publicly funded gene sequencing efforts in the United States, Francis Collins, director of the National Human Genome Research Institute (NHGRI) told his advisory council this week.
Until recently, no researcher would have considered taking on the burden of another mammal's genome while jammed sequencing centers worked through the human and mouse. But high-throughput labs at the Whitehead Institute in Boston, Baylor College of Medicine in Houston, Washington University in St. Louis, and the Joint Genome Institute in Walnut Creek, California, have added new machines and increased their capacity some 10-fold, says Robert Waterston, director of the Washington University center. Now their output, plus that of Britain's Sangre Center, is "enough to do a working draft of a mammalian genome in 4 to 5 months," Waterston told the council. As a result, the NHGRI-funded centers want to sequence the rat, mouse, and human genomes in parallel--if NHGRI and the National Heart, Lung, and Blood Institute can carve out funds from the still undecided 2001 budget.
Another mammalian sequence, says Raju Kucherlapati from Albert Einstein College of Medicine in New York City, would "really help with [interpreting] the human genome."