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10 April 2014 11:44 am ,
Vol. 344 ,
The Pyrenean ibex, an impressive mountain goat that lived in the central Pyrenees in Spain, went extinct in 2000. But a...
Tight budgets are forcing NASA to consider turning off one or more planetary science projects that have completed their...
Ebola is not a stranger to West Africa—an outbreak in the 1990s killed chimpanzees and sickened one researcher. But the...
In an as-yet-unpublished report, an international panel of geoscientists has concluded that a pair of deadly...
Tropical disease experts tried and failed before to eradicate yaws, a rare disfiguring disease of poor countries. Now,...
Since 2002, researchers have reported that agricultural communities in the hot and humid Pacific Coast of Central...
Balkan endemic kidney disease surfaced in the 1950s and for decades defied attempts to finger the cause. It occurred...
- 10 April 2014 11:44 am , Vol. 344 , #6180
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Calling All DNA Chip Data
31 July 2000 6:00 pm
Researchers who've joined the stampede to use glass chips dotted with specks of genes to study how cells work now have a place to share their growing piles of data. Last week, the National Center for Biotechnology Information (NCBI) rolled out a new public Web database that will archive results from DNA microarrays and other hot lab tools for seeing the expression of thousands of genes at once.
The Gene Expression Omnibus, or GEO, will store data from any type of gene expression test, including both manufactured and homemade chips, for free. Scientists log in, describe the test type, and post results--tables showing gene expression levels--and reference images of their arrays. GEO will also archive results from a series of tests, such as the dose-response relationship of a toxin. You can't do much of a search just yet, as the first stage is simply to build a stash of data. But within a few months, "you'll be able to query in different ways," says NCBI's Alex Lash. He hopes that, as with the GenBank gene database, people will eventually submit even data they don't necessarily plan to publish.
At least two other public microarray databases are also in the works: The National Center for Genome Resources in Santa Fe, New Mexico, plans to open a database this fall, and the U.K.'s European Bioinformatics Institute (EBI) hopes to launch one next year.