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12 December 2013 1:00 pm ,
Vol. 342 ,
The iconic 125-year-old Lick Observatory on Mount Hamilton near San Jose, California, is facing the threat of closure...
Recent results from the Curiosity Mars rover have helped scientists formulate a plan for the next phase of its mission...
A new, remarkably powerful drug that cripples the hepatitis C virus (HCV) came to market last week, but it sells for $...
In pretoothbrush populations, gumlines would often be marred by a thick, visible crust of calcium phosphate, food...
Evolutionary biologists have long studied how the Mexican tetra, a drab fish that lives in rivers and creeks but has...
Victorian astronomers spent countless hours laboriously charting the positions of stars in the sky. Such sky mapping,...
In an ambitious project to study 1000 years of sickness and health, researchers are excavating the graveyard of the now...
Stefan Behnisch has won awards for designing science labs and other buildings that are smart, sustainable, and...
- 12 December 2013 1:00 pm , Vol. 342 , #6164
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NIH Expands Definition of Human Embryonic Stem Cell
19 February 2010 4:32 pm
The National Institutes of Health is slightly expanding its definition for what constitutes a human embryonic stem cell. Currently, for purposes of including cells in its stem cell registry, NIH guidelines define the cells as "derived from the inner cell mass of blastocyst stage human embryo." As proposed tomorrow in the Federal Register, the definition will cover "early stage embryos up to and including" the blastocyst stage.
The change has come primarily in response to an application by Advanced Cell Technology (ACT) of Worcester, Massachusetts. "We came to understand recently that there was interest in deriving cells from earlier-stage embryos," says NIH's Lana Skirboll. ACT wants to list on the registry five cell lines derived from the earlier, morula stage. Skirboll says that, in addition, three lines submitted by Harvard Medical School's George Daley were derived from embryos that hadn't reached blastocyst stage. Approval for them has been put on hold pending acceptance of the revised definition.
So far the registry has approved 40 lines. The change is a small one, Skirboll says; There is no change in ethical guidelines for deriving cells.