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10 April 2014 11:44 am ,
Vol. 344 ,
The Pyrenean ibex, an impressive mountain goat that lived in the central Pyrenees in Spain, went extinct in 2000. But a...
Tight budgets are forcing NASA to consider turning off one or more planetary science projects that have completed their...
Ebola is not a stranger to West Africa—an outbreak in the 1990s killed chimpanzees and sickened one researcher. But the...
In an as-yet-unpublished report, an international panel of geoscientists has concluded that a pair of deadly...
Tropical disease experts tried and failed before to eradicate yaws, a rare disfiguring disease of poor countries. Now,...
Since 2002, researchers have reported that agricultural communities in the hot and humid Pacific Coast of Central...
Balkan endemic kidney disease surfaced in the 1950s and for decades defied attempts to finger the cause. It occurred...
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NIH Expands Definition of Human Embryonic Stem Cell
19 February 2010 4:32 pm
The National Institutes of Health is slightly expanding its definition for what constitutes a human embryonic stem cell. Currently, for purposes of including cells in its stem cell registry, NIH guidelines define the cells as "derived from the inner cell mass of blastocyst stage human embryo." As proposed tomorrow in the Federal Register, the definition will cover "early stage embryos up to and including" the blastocyst stage.
The change has come primarily in response to an application by Advanced Cell Technology (ACT) of Worcester, Massachusetts. "We came to understand recently that there was interest in deriving cells from earlier-stage embryos," says NIH's Lana Skirboll. ACT wants to list on the registry five cell lines derived from the earlier, morula stage. Skirboll says that, in addition, three lines submitted by Harvard Medical School's George Daley were derived from embryos that hadn't reached blastocyst stage. Approval for them has been put on hold pending acceptance of the revised definition.
So far the registry has approved 40 lines. The change is a small one, Skirboll says; There is no change in ethical guidelines for deriving cells.