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An animal rights group known as the Nonhuman Rights Project filed lawsuits in three New York courts this week in an...
Researchers have been hot on the trail of the elusive Denisovans, a type of ancient human known only by their DNA and...
Thousands of scientists in the Russian Academy of Sciences (RAS) are about to lose their jobs as a result of the...
Dyslexia, a learning disability that hinders reading, hasn't been associated with deficits in vision, hearing, or...
Exotic, elusive, and dangerous, snakes have fascinated humankind for millennia. They can be hard to find, yet their...
Researchers have sequenced and analyzed the first two snake genomes, which represent two evolutionary extremes. The...
Snake venoms are remarkably complex mixtures that can stun or kill prey within minutes. But more and more researchers...
At age 30, Dutch biologist Freek Vonk has built up a respectable career as a snake scientist. But in his home country,...
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CSI's Latest Clue—Bacteria
15 March 2010 3:24 pm
Criminals already have to be careful not to leave fingerprints or DNA that could incriminate them. But they might want to carry hand sanitizer, too, according to a new study that suggests a new way to finger perpetrators from their skin bacteria.
The human body hosts hundreds of bacterial species that perform various salubrious housekeeping chores, from aiding digestion to helping the immune system identify foreign invaders. Every person—even an identical twin—has a unique distribution of bacteria on various body areas. Now some researchers are suggesting that these individual differences could lead to the development of new crime-solving tools.
Biologist Noah Fierer of the University of Colorado, Boulder, and colleagues have been mapping the composition of bacteria that inhabit various body sites. They and others have discovered that the human body actually comprises a couple dozen mini-ecosystems. Not only are there separate colonies inside and out, but skin harbors a multitude of bacterial colonies. Bacteria found on the smooth, dry forearm, for example, are as dissimilar from those in the moist, warm armpit as deserts are from rainforests, according to researchers at the National Institutes of Health.
What's more, these colonies vary from person to person, and they are stable over time. Because only 13% of bacterial colonies on the palm are shared between any two individuals, Fierer and colleagues wondered if bacteria from palms and fingertips could be put to forensic use.
To determine how similar a person's fingertip bacteria are to bacteria left on computer keys, the team took swabs from three computer keyboards and compared bacterial gene sequences with those from the fingertips of the keyboard owners. Today in the Proceedings of the National Academy of Sciences, they conclude that enough bacteria can be collected from even small surfaces such as computer keys to link them with the hand that laid them down.
The researchers then tested how well such a technique could distinguish the person who left the bacteria from the general population. They sampled bacteria from nine computer mice and from the nine mouse owners. They also collected information on bacterial communities from 270 hands that had never touched any of the mice. In all nine cases, the bacteria on the mice were far more similar to the mouse-owners' hands than to any of the 270 strange hands. The researchers also found that bacteria will persist on a computer key or mouse for up to 2 weeks after it has been handled.
Fierer says the characteristics of a person's bacterial colonies are so persistent that "if you wash your hands, it only takes a few hours for a community to reestablish itself." That's probably because the bacteria are living in deeper skin layers, he says. Fierer adds that it may be possible to retrieve useful amounts of bacterial gene sequences from textured surfaces that won't yield fingerprints.
Geneticist Elizabeth Grice of the National Human Genome Research Institute in Bethesda, Maryland, cautions that "it is difficult to determine at this point how unique a person's skin microbiota is because so few people's skin microbiomes have been fully characterized."
The team agrees that their research is preliminary and that the method needs to be tested on other surfaces. But Fierer points out that it took 50 years to figure out the nuances of standard fingerprinting. "The idea is that we leave this trail of bacteria behind us, and that trail may be informative."