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5 December 2013 11:26 am ,
Vol. 342 ,
An animal rights group known as the Nonhuman Rights Project filed lawsuits in three New York courts this week in an...
Researchers have been hot on the trail of the elusive Denisovans, a type of ancient human known only by their DNA and...
Thousands of scientists in the Russian Academy of Sciences (RAS) are about to lose their jobs as a result of the...
Dyslexia, a learning disability that hinders reading, hasn't been associated with deficits in vision, hearing, or...
Exotic, elusive, and dangerous, snakes have fascinated humankind for millennia. They can be hard to find, yet their...
Researchers have sequenced and analyzed the first two snake genomes, which represent two evolutionary extremes. The...
Snake venoms are remarkably complex mixtures that can stun or kill prey within minutes. But more and more researchers...
At age 30, Dutch biologist Freek Vonk has built up a respectable career as a snake scientist. But in his home country,...
- 5 December 2013 11:26 am , Vol. 342 , #6163
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Planned Trial of Diabetes Drug Avandia Runs Aground
21 July 2010 4:39 pm
A large study to test the safety of the controversial diabetes drug Avandia has been put on partial hold by the Food and Drug Administration. The FDA held a hearing on the safety of Avandia last week. Some scientists argue that the drug persistently, if modestly, increases the risk of heart attacks in diabetes patients. But other scientists, as well as the drug's maker, GlaxoSmithKline, challenge those results. The TIDE trial was designed to clear up lingering doubts about the drug but would take at least 6 years to complete. And today, FDA informed Glaxo that it was not allowed to enroll any new patients in TIDE, although patients already enrolled can continue.
Science will report on the TIDE trial in the 23 July issue, which appears online tomorrow.