- News Home
6 March 2014 1:04 pm ,
Vol. 343 ,
Since 2000, U.S. government health research agencies have spent almost $1 billion on an effort to churn out thousands...
Magdalena Koziol, a former postdoc at Yale University, was the victim of scientific sabotage. Now, she is suing the...
Antiretroviral drugs can protect people from becoming infected by HIV. But so-called pre-exposure prophylaxis, or PrEP...
Two studies show that eating a diet low in protein and high in carbohydrates is linked to a longer, healthier life, and...
Considered an icon of conservation science, researchers at World Wildlife Fund (WWF) headquarters in Washington, D.C.,...
The new atlas, which shows the distribution of important trace metals and other substances, is the first product of...
Early in April, the first of a fleet of environmental monitoring satellites will lift off from Europe's spaceport in...
- 6 March 2014 1:04 pm , Vol. 343 , #6175
- About Us
Video: X-rays Paint Whole-Cell Portraits
17 February 2012 6:59 pm
VANCOUVER, CANADA—Imagine photographing every seed in a watermelon without cutting a single slice. Scientists can use x-rays to create similar internal portraits of whole cells, they reported here this morning at the annual meeting of the American Association for the Advancement of Science (which publishes ScienceNOW). Like performing a cellular CT scan, researchers rapidly freeze a cell and snap its x-ray image once every 100 milliseconds. They can reconstruct an entire cell from 90-200 images in about 5 minutes. Using the differing light-absorption properties of organelles—the cell’s functional structures—the scientists can automatically identify and color-code this inner machinery, like in the T cell shown above (the nucleus is bright blue, mitochondria are pink, and lysosomes are yellow). Researchers can use the technique to count and calculate the volume of organelles, and even measure how much hemoglobin malarial parasites consume inside red blood cells. Peering inside a whole cell without the laborious slicing and staining of electron microscopy makes x-ray imaging quick, quantitative, and decidedly less mess.
See more Videos