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6 March 2014 1:04 pm ,
Vol. 343 ,
Magdalena Koziol, a former postdoc at Yale University, was the victim of scientific sabotage. Now, she is suing the...
Antiretroviral drugs can protect people from becoming infected by HIV. But so-called pre-exposure prophylaxis, or PrEP...
Two studies show that eating a diet low in protein and high in carbohydrates is linked to a longer, healthier life, and...
Considered an icon of conservation science, researchers at World Wildlife Fund (WWF) headquarters in Washington, D.C.,...
The new atlas, which shows the distribution of important trace metals and other substances, is the first product of...
Early in April, the first of a fleet of environmental monitoring satellites will lift off from Europe's spaceport in...
Since 2000, U.S. government health research agencies have spent almost $1 billion on an effort to churn out thousands...
- 6 March 2014 1:04 pm , Vol. 343 , #6175
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ScienceShot: Worms Enter the Synthetic Age
12 August 2011 10:55 am
Designer proteins aren't just for bacteria anymore. For the first time, scientists have engineered a whole animal to build its proteins with a synthetic amino acid. The early adopter is a microscopic worm known as Caenorhabditis elegans. Researchers had previously tweaked the genome of the Escherichia coli bacterium to code for 21 amino acids instead of the typical 20, and now another group has done the same with C. elegans. To track which of the worm's cells made proteins that utilized this extra, artificial building block, the team tagged it with a glowing cherry-red dye. And sure enough, cells that went synthetic glowed red, the researchers report this week in the Journal of the American Chemical Society. They now hope to create worms with artificial amino acids that can be controlled by light or specific chemicals: a toolkit that would allow researchers to switch specific cells or molecules on and off.
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