Bacteria Add Fluorine to Natural Product Medicines

Staff Writer

Fluorine is key to the activity of top-selling small molecule drugs. But it's difficult to add the element to large molecules without destroying their function. Now, researchers led by Michelle Chang at the University of California, Berkeley, have shown that they can engineer bacteria to incorporate fluorine into complex compounds, the sorts that make up antibiotics, antifungals, and insecticides.

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Posted in Biology, Chemistry