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6 March 2014 1:04 pm ,
Vol. 343 ,
Antiretroviral drugs can protect people from becoming infected by HIV. But so-called pre-exposure prophylaxis, or PrEP...
Two studies show that eating a diet low in protein and high in carbohydrates is linked to a longer, healthier life, and...
Considered an icon of conservation science, researchers at World Wildlife Fund (WWF) headquarters in Washington, D.C.,...
The new atlas, which shows the distribution of important trace metals and other substances, is the first product of...
Early in April, the first of a fleet of environmental monitoring satellites will lift off from Europe's spaceport in...
Since 2000, U.S. government health research agencies have spent almost $1 billion on an effort to churn out thousands...
Magdalena Koziol, a former postdoc at Yale University, was the victim of scientific sabotage. Now, she is suing the...
- 6 March 2014 1:04 pm , Vol. 343 , #6175
- About Us
19 April 1999 6:30 pm
Today is the birthday of Ines Mandl, a U.S. biochemist who conducted pioneering research on enzymes and elastic tissue that led to advances in the understanding of pulmonary emphysema.
Mandl, who was born in 1917, investigated collagenases--a group of about 20 enzymes that can break down collagen into a soluble form--and was the first to isolate and purify one of the enzymes. As director of the obstetrics/gynecology laboratories of Delafield Hospital (affiliated with Columbia University), Mandl studied respiratory distress and emphysema in newborn babies and identified the role of elastin, an elastic tissue in the lungs. She showed that patients with emphysema had deterioration of elastin, which destroyed their lung tissue. Cigarette smoking, she found, also damaged elastin.
In 1972, Mandl founded the journal Connective Tissue Research.
Source: Benjamin F. Shearer and Barbara S. Shearer, Notable Women in the Physical Sciences: A biographical dictionary (Greenwood Press, 1997).