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Category: Cell Biology

Stress May Keep Neurons Down

For days after a traumatic event, mice seem to exhibit decreased levels of a key neurotransmitter, according to a report in the current Nature. The finding may help explain how...

New Flu Vaccine Copies Itself

A new DNA vaccine can pump out unprecedented amounts of flu protein into the bloodstream of mice, rendering them resistant to the flu virus. The experimental vaccine, described in next...

Genes That Keep Clocks Ticking

Fruit flies, like people, follow a daily schedule of eating, resting, and other activities. Now neurogeneticists have discovered two genes that appear to be long-sought missing pieces in the biological...

New Gear in Mouse Clock?

New proteins found in the eye may explain how mammals keep their internal clocks in synch with the sun, according to a paper in this week's Proceedings of the National...

Neuron Complexity Predicts Seizures

Scientists have crafted a tool for predicting epileptic seizures with equations from chaos theory. The finding, reported next month in Physical Review Letters, could provide an early warning system and...

TB Protein May Aid Drug Delivery

ATLANTA--A cell-piercing protein from the bacterium that causes tuberculosis (TB) could serve as a delivery system for future medicines. At the American Society for Microbiology's annual meeting here researchers reported...

Wild Arterial Rides

Blood is known to spiral as it flows through arteries, but researchers at a Royal Academy of Engineering conference announced yesterday in London that these helical streams themselves whirl like...

How Arthritis Gets a Toehold

Walking in high heels does more than just spur bunions and lower back pain--it also may lead to bum knees, researchers report in tomorrow's Lancet. Joints are normally cushioned by...

No Neuron Growth From Alzheimer's Gene

Scientists have found that one form of a gene linked to Alzheimer's disease fails to get mouse nerve cells to grow, although a more common form does stimulate growth. The...

Protein Legacy From Celibate Cells

With no thoughts of having children, monks and nuns and worker bees can dedicate themselves to a life of selflessly serving others. Now, researchers have put abstinence to work in...
30 April 1998 | ScienceNOW

New Clue to How Anthrax Kills

The deadly disease anthrax has been much in the news lately--thanks largely to fears that rogue leaders or terrorists will attempt to wage germ warfare with the anthrax bacillus. But...
27 April 1998 | ScienceNOW

Teflon Heart

A nagging problem with artificial hearts and other medical implants is that blood proteins stick to them, gumming them up and sometimes leading to dangerous blood clots. Now scientists have...
17 April 1998 | ScienceNOW

Fast Reactions From Tiny Mixer

Scientists will soon be able to get a peek at exactly what proteins do in the first few microseconds of folding. A report in an upcoming issue of Physical Review...
16 April 1998 | ScienceNOW

The Moon Through The Trees

The diameter of tree seedlings may fluctuate with the tides, according to a paper in tomorrow's Nature. The changes are barely perceptible--only a few hundredths of a millimeter--but scientists say...
16 April 1998 | ScienceNOW

Deadly Path to a Large Heart

Like the waistband in your favorite old pajamas, overstressed hearts often lose their elasticity and their ability to pump blood efficiently--a condition called congestive heart failure. The tired hearts are...
14 April 1998 | ScienceNOW

Sponge Poison Kills Cell Motors

A toxin that jams a common cellular motor has been discovered in a marine sponge. The compound, described in the current issue of Science, could perhaps be modified to keep...

Structure of Potassium Channel Solved

Scientists have worked out the structure of the potassium ion channel, a sluice in the cell membrane that enables neurons to transmit electrical signals. The accomplishment, reported in the current...

Sharp Views from Dissonant Ultrasound

Scientists have invented a new type of ultrasound probe that jostles tissue or other material then listens for sounds generated by the movement. The technique, described in today's Science, can...

First Working Bionic Cell

In the 1970s TV drama "The Six Million Dollar Man," the show's opening credits feature a team of scientists creating artificial limbs and an eye that, unlike today's prosthetic devices,...
26 March 1998 | ScienceNOW

A Nerve-Wracking Discovery

Today is the 87th birthday of Sir Bernard Katz, a German-born English physiologist who elucidated how nerve cells transmit signals. Although it was known that neurons release acetylcholine at their...
17 March 1998 | ScienceNOW

New Nerves Sprout New View of Brain

Scientists have found that the brains of adult primates are not a dead end for nerve growth, as popularly thought, but in fact are able to grow new nerve cells....

New Muscle Bred in the Bone

Molecular and developmental biologists have discovered a potentially useful source of replacement muscle for people suffering from muscular dystrophy. As reported in today's issue of Science, experiments in mice show...

Assisted Suicide May Help Transplants Survive

Transplanted organs rarely get a hero's welcome in their new home--in fact, they are often attacked viciously by the host's immune system. Researchers have long known that a follow-up infusion...

How Lithium Quells a Manic Riot

Although lithium chloride has been the drug of choice for treating manic depression for nearly a half-century, nobody has known how the drug acts to quell the turbulent mood swings...
24 February 1998 | ScienceNOW

Going for the Jugular Against Parkinson's

A potential therapy for Parkinson's disease may lie in an unusual location: the carotid body, a small organ in the neck. In the February issue of Neuron, José López-Barneo and...
20 February 1998 | ScienceNOW

New Appetite-Boosting Peptides Discovered in Rats

Researchers have discovered a potential new target for appetite-altering drugs. In today's issue of Cell, a team led by Masashi Yanagisawa of the University of Texas Southwestern Medical Center in...
18 February 1998 | ScienceNOW

A Pain in the Immune System

PHILADELPHIA--Immune system cells in the spinal cord may help trigger excruciating, hard-to-treat pain. The finding, reported last week at the annual meeting of the American Association for the Advancement of...
18 February 1998 | ScienceNOW

The Secret of Resistant Leukemia

A rare, untreatable type of leukemia appears to be due to a mutant cell receptor that binds one signaling molecule so tightly that it is deaf to the signals that...
17 February 1998 | ScienceNOW

Tugging at a Cell's Heartstrings

PHILADELPHIA--Researchers have observed cells hastily setting up factories for producing proteins when the surface of the cell is pulled or twisted. The findings, reported Friday evening at the annual meeting...
13 February 1998 | ScienceNOW

All Wound Up Over DNA

PHILADELPHIA--DNA is a contortionist extraordinaire: As much as a meter can twist into a bundle small enough to squeeze inside a cell's nucleus. Now researchers have wound a stretch of...
10 February 1998 | ScienceNOW

RNA World Gets Flamed

SAN DIEGO--RNA, the genetic molecule that many researchers think was the basis of the first life, might not have been able to take the heat in the early world. A...
6 February 1998 | ScienceNOW

Prions' Deadly New Twist

Prions, common proteins that when misfolded are thought to cause "mad cow disease" and its human equivalent, may have another deadly form. In today's issue of Science, researchers show that...
6 February 1998 | ScienceNOW

Cardiology by the Numbers

A mathematical analysis of heartbeat patterns can detect certain heart disorders with unerring accuracy. Previous mathematical tools for diagnosing heart disease have generally not been reliable enough to use clinically....
28 January 1998 | ScienceNOW

Severed Nerves Found in Multiple Sclerosis

The clumsiness, blurred vision, and other symptoms of multiple sclerosis have long been blamed on the loss of fatty insulation around nerve fibers. Now scientists report that many of these...
20 January 1998 | ScienceNOW

New MS Treatment for Mice

Uric acid appears to be a wonder drug in mice: It wards off a disease that resembles multiple sclerosis (MS), an autoimmune disorder in people, and allows partially paralyzed mice...
16 January 1998 | ScienceNOW

Paparazzi of the DNA World

An x-ray snapshot of crystallized DNA polymerase, an enzyme that copies our genetic blueprint, has revealed a remarkable ability to function while in crystal form, according to a report in...
15 January 1998 | ScienceNOW

Knees Help Set Body's Clock

Human circadian rhythms that govern sleep, body temperature, and other regular cycles apparently can be influenced by shining bright light on the body--even if the eyes cannot see it. The...
13 January 1998 | ScienceNOW

Fountain of Cellular Youth

A team of researchers reported today that it has found a way to extend the lifetime of several types of cells. The studies, which used an enzyme called telomerase, also...
12 January 1998 | ScienceNOW

Light-Sensing Protein Found in Brain

Deep within the brains of frogs, in a part of their anatomy where the sun never shines, appears to be a protein that catalyzes biochemical reactions in response to light....
8 January 1998 | ScienceNOW

Do Botched Proteins Add Up to Alzheimer's?

Scientists have a provocative new explanation for what may cause Alzheimer's disease in the majority of patients: a mistake in how certain proteins are made. The findings, reported in tomorrow's...
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