Skin Cells Become Liver Cells

24 February 2014 1:00 pm
Human liver

Department of Histology, Jagiellonian University Medical College

Human liver

Liver transplants may no longer be the only option for patients with the failing organ. Scientists have successfully reprogrammed skin cells into fully functioning liver cells, according to a study published yesterday in Nature. The skin cells were first transformed using chemical compounds and gene reprogramming to resemble endoderm cells—embryonic cells that mature into the body’s multiple organs. They were then further transformed into liver cells and transplanted into mice with liver failure, where they flourished, continued growing, and became functional liver cells.

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